Obesity Research & Peroxynitrite Decomposition Catalysts Sample Preparation Using HemogloBind™

MONMOUTH JUNCTION, N.J. - May 6, 2015 - PRLog -- MONMOUTH JUNCTION, NJ – A research article in the journal Archives of Biochemistry & Biophysics (http://www.sciencedirect.com/science/article/pii/S0003986115001988) cites Biotech Support Group’s HemogloBind™ (http://www.biotechsupportgroup.com/node/75) sample preparation reagent to deplete hemoglobin (Hb) from lysed red blood cells. The article states:

"Blood plasma (50 µl) was mixed with HemogloBind (50 µl) to remove hemoglobin from lysed red blood cells."

Plasma hemoglobin is depleted using Biotech Support Group's HemogloBind™ to extract hemoglobin from lysed red blood cells. Plasma concentration of high-density lipoprotein (HDL), total cholesterol and triacylglycerol (TAG) is obtained. Precipitation using polyethylene glycol (PEG) of beta-lipoproteins such as very low-density lipoprotein (VLDL) and low-density lipoprotein(LDL) from HDL fractions is performed.

“We are pleased with this data on peroxynitrite decomposition catalysts. HemogloBind™ minimizes hemoglobin interference from blood samples and allows research on cholesterol proteins” states Swapan Roy, Ph.D., President and Founder of Biotech Support Group.

About Biotech Support Group LLC
Biotech Support Group LLC is a leading provider of proteomic, metabolomic and genomic sample preparation and enrichment products and services. It’s principal products include: AlbuVoid™ & AlbuSorb™ for albumin depletion, Cleanascite™ for lipid adsorption and clarification, HemogloBind™ & HemoVoid™ for hemoglobin removal, NuGel™ for functional & chemical proteomics, and ProCipitate™ for nucleic acid isolation. For more information, go to http://www.biotechsupportgroup.com

Contact:
Dr. Swapan Roy & Matthew Kuruc
Biotech Support Group LLC
1 Deer Park Drive, Suite M
Monmouth Junction NJ 08852
732-274-2866 Worldwide
800-935-0628 North America
sales@biotechsupportgroup.com
http://www.biotechsupportgroup.com

Reference

Johns, Michael, et al. "SR-135, a peroxynitrite decomposing catalyst, enhances β-cell function and survival in B6D2F1 mice fed a high fat diet (http://www.sciencedirect.com/science/article/pii/S0003986115001988)."Archives of Biochemistry and Biophysics (2015).

Suggested References

Ding, R., et al. "Peroxynitrite decomposition catalyst prevents matrix metalloproteinase-9 activation and neurovascular injury after hemoglobin injection into the caudate nucleus of rats." Neuroscience 297 (2015): 182-193.

Kosower, Nechama S., Rela L. Koppel, And Edward M. Kosower. "Sensitivity of hemoglobin thiol groups within red blood cells of rat during oxidation of glutathione." European Journal of Biochemistry 77.3 (1977): 529-534.