BellBrook Labs Webinar: Analyzing Kinase Inhibitor Residence Times using Transcreener® ADP Assay

GÖTTINGEN, Germany - April 15, 2015 - PRLog -- Join us on April 29th at 12 EDT to learn about  Analyzing Kinase Inhibitor Residence Times using the Transcreener® ADP Assay.

BellBrook Labs' senior application scientist Meera Kumar will present on the use of the Transcreener® ADP assay to determine the residence time of an inhibitor during its interaction with a kinase. This measure is highly relevant for assessing the durable pharmacologic effects of a drug candidate and can be easily incorporated into your routine secondary screening studies.

http:RegisterNow (https://attendee.gotowebinar.com/register/1138866813146785026?_cldee=YS5zY2h1bHpAbW9iaXRlYy5kZQ%3d%3d&utm_source=ClickDimensions&utm_medium=email&utm_campaign=WBN%20-%20Residence%20Time) and join us on Wednesday, April 29 at 12 EDT.

Want to learn more?  View the downloadable Application Note or contact us at info@mobitec.com .

Transcreener® Performance with a Positive Readout ...

The Transcreener® ADP² Fluorescent Intensity (FI) Assay produces a simple fluorescent intensity output which can be read on even the most basic fluorescence readers typically found in academic and therapeutic research labs as well as more complex multimode plate readers. It is a simple one-step homogenous detection assay, and is flexible with regard to ATP concentration (0.1 to 1,000 µM ATP). The assay provides excellent signal at low substrate conversion, with a Z' > 0.7 at 2.5% ATP conversion using 1 µM ATP.

• UNIVERSAL: detect any ADP-producing enzyme, using any substrate.
• SINGLE ADDITION: one-step, simple mix and read format.
• SENSITIVE: Z' > 0.7 at low ATP conversion.
• POSITIVE FI READOUT: use with any fluorescence plate reader.

About Bellbrook Labs

BellBrook Labs is dedicated to providing the pharmaceutical industry with enabling screening tools to accelerate the discovery of more effective therapies. As a small, R&D-driven company, BBL identifies areas where there is a strong need but a significant technical hurdle, and then BBL develops a solution. The company is focused on taking creative approaches to new product development and to continually improving the level of service provided to our customers. BellBrook is undergoing a big change with the launch of the first two iuvo™ products and the Invasion Assay Service in 2010. The company has built its reputation on Transcreener®, a biochemical assay platform, and with iuvo BBL is introducing completely new way to perform cellular assays. www.bellbrooklabs.com

About MoBiTec GmbH

MoBiTec GmbH (Goettingen, Germany) is a privately held company (founded in 1987) that offers research tools for molecular and cell biology. Products include DNA vectors for cloning and expression, cell transfection reagents and cell culture tools, immobilized and soluble enzymes, products for genomics and proteomics research, numerous antibodies and recombinant proteins, superior fluorescence reagents and kits, affinity chromatography products, as well as general laboratory equipment.

In parallel to its own product lines, MoBiTec distributes products from international companies in Germany. MoBiTec products are distributed worldwide, in Germany from their home office, in other countries by distributors.
www.mobitec.com