MoBiTec Offers "Fluoppi", Fluorescent Image-Based Protein-Protein Interaction (PPI) Analysis

GÖTTINGEN, Germany - Oct. 13, 2014 - PRLog -- MoBiTec GmbH, Germany, gladly announces the availability of Fluoppi (Fluorescent based technology detecting Protein-Protein Interactions). The product presents a novel technology to detect Protein-Protein Interaction (PPI) in living cells. It is developed by the Japanese company Amalgaam and commercialized international by US-based MBLI. Fluoppi is available to customers in Germany through MoBiTec GmbH.

Image based Protein-Protein interaction (PPI) analysis

• Detect PPI as fluorescent " Foci " in living cells
• Reversible foci-formation
• Easy -to-handle

Fluoppi is a tag technology. Tetramer fluorescent protein (FP-tag) and Assembly helper tag (Ash-tag) are genetically fused to Protein X and Y, respectively. For the FP-tag, tetramer Green Fluorescent protein Azami Green (hAG) can be used. For the  Ash-tag, PB1 domain of p62 can be used. PB1 is 102 amino acid length domain which has the capability of electrostatically homo-oligomerization in a head to tail manner. In our  in vitro Fluorescence correlation spectroscopy analysis, Ash-tag behaved as tetramer to octomer in diluted solution.

For detailed information please see:

http://www.mobitec.com/cms/products/bio/08_screening/fluo...

Fluoppi is available as of now.

About MBLI

Established in 1993, MBL International Corporation (MBLI) is a leading life science company focused on providing high quality, innovative, solutions-based products for both life science research and clinical diagnostics. Our products are used widely in academic research institutions, pharmaceutical and biotechnology companies, government agencies as well as hospital and reference laboratories.

About MoBiTec GmbH

MoBiTec GmbH (Goettingen, Germany) is a privately held company (founded in 1987) that offers research tools for molecular and cell biology. Products include DNA vectors for cloning and expression, cell transfection reagents and cell culture tools, immobilized and soluble enzymes, products for genomics and proteomics research, numerous antibodies and recombinant proteins, superior fluorescence reagents and kits, affinity chromatography products, as well as general laboratory equipment.

In parallel to its own product lines, MoBiTec distributes products from international companies in Germany. MoBiTec products are distributed worldwide, in Germany from their home office, in other countries by distributors.