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BioVision Introduces Three New Assay Kits: Monoamine Oxidase Activity & Inhibitor Screening Kits

BioVision is delighted to introduce three new assay kits: MAO-A & MAO-B Inhibitor Screening Kits, only specific kits in market to screen MAO-A or MAO-B inhibitors and Monoamine Oxidase Activity Assay Kit to quantify the enzymatic activity of MAO!

 
 
MAO Activity Assay Kit
MAO Activity Assay Kit
PRLog - Mar. 31, 2014 - MILPITAS, Calif. -- Monoamine oxidases (MAO) are a family of enzymes that can oxidize a wide variety of endogenous primary amines. Two isoforms, MAO-A and MAO-B, have been identified based on their substrate, inhibitor specificity, and tissue localization. Clonogenic studies have shown that these two isozymes have similar catalytic characteristics, yet their amino acid sequences are different. MAO-A favors Serotonin, Norerpinephrine and Dopamine as substrates, while phenylethylamine and benzylamine are MAO-B preferred substrates. MAO-A and MAO-B are mitochondrial-bound enzymes that are ubiquitously expressed throughout the brain and other tissues. Imbalance of MAOs levels has been associated with schizophrenia, depression, attention deficit and other disorders. MAO-A has been implicated in panic, anxiety and depression, whereas MAO-B defects result in Alzheimer’s and Parkinson’s diseases.

Monoamine Oxidase Activity (Total MAO/MAO-A/MAO-B) Fluorometric Assay Kit (Catalog # K795-100) - 100 assays: BioVision’s Monoamine Oxidase Activity (Total MAO/MAO-A/MAO-B) assay is a sensitive assay to detect total monoamine oxidase activity as well as MAO-A and MAO-B isoenzyme activities separately in the presence of Clorgyline and Selegiline - specific inhibitors for MAO-A and MAO-B, respectively. The assay is based on the fluorometric detection of hydrogen peroxide, one of the byproducts generated during the oxidative deamination of the MAO substrate (Tyramine).

Key Features and Benefits of the Kit:

- Rapid & convenient
- Useful for measuring total monoamine oxidase activity, monoamine oxidase A or monoamine oxidase B activity in various biological samples
- Compatible with various sample types such as biological fluids: serum & plasma, animal tissues such as brain, heart, liver, kidney, lung & cell lines (fibroblasts) etc.
- Detects MAO activity as low as 5 µU in a variety of samples
- Fluorometric quantification (Ex/Em = 535/587 nm)
- Includes MAO-A Inhibitor, Clorgyline & MAO-B Inhibitor, Selegiline

For more information, please visit
http://www.biovision.com/monoamine-oxidase-activity-total...

Monoamine Oxidase A (MAO-A) Inhibitor Screening Kit (Fluorometric (Catalog # K796-100) - 100 assays: Several MAO-A specific inhibitors such as clorgyline, brofaromine, toloxatone, tetrindole, etc. have been used as antidepressants, but their usage has been limited due to side effects. BioVision’s MAO-A Inhibitor Screening Kit offers a simple assay to screen MAO-A inhibitors which is based on the fluorometric detection of hydrogen peroxide, one of the byproducts generated during the oxidative deamination of MAO substrate (Tyramine).

Key Features and Benefits of the kit:
- Rapid & simple
- sensitive
- High-throughput
- Useful for screening/studying/characterizing MAO-A inhibitors
- Fluorometric quantification (Ex/Em = 535/587 nm)
- Includes inhibitor control, clorgyline

For more information, please visit:
http://www.biovision.com/monoamine-oxidase-a-mao-a-inhibi...

Monoamine Oxidase B (MAO-B) Inhibitor Screening Kit (Fluorometric)(Catalog # K797-100) - 100 assays: Specific MAO-B inhibitors such as selegiline, & rasagiline have been used to treat Parkinson’s patients, but their benefits are considered rather modest. BioVision’s MAO-B Inhibitor Screening Kit offers a simple assay to screen MAO-B inhibitors, which is based on the fluorometric detection of hydrogen peroxide, one of the byproducts generated during the oxidative deamination of MAO substrate (Tyramine).

Key Features and Benefits of the kit:
- Simple & Convenient
- Reliable & Sensitive
- High-throughput
- Useful for screening/studying/characterizing MAO-B inhibitors
- Fluorometric quantification (Ex/Em = 535/587 nm)
- Includes inhibitor control, selegiline

For more information, please visit:
http://www.biovision.com/monoamine-oxidase-b-mao-b-inhibi...


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Source:BioVision, Inc.
City/Town:Milpitas - California - United States
Industry:Biotech
Tags:monoamine oxidase, mao-b inhibitor, mao-a inhibitor, mao, mao-b
Shortcut:prlog.org/12303297
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