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NAMSR Investigate: New blood test predicts Alzheimer's, dementia

Researchers have developed a new blood test that can predict with 90% accuracy whether a healthy person will develop Alzheimer's or cognitive decline within 3 years.

PRLog - March 13, 2014 - ARLINGTON, Va. -- Researchers have developed a new blood test that can predict with 90% accuracy whether a healthy person will develop Alzheimer's or cognitive decline within 3 years. They report how they identified and validated the 10 biomarkers that form the basis of the test in a study published in Nature Medicine.

Study leader Howard J. Federoff, a professor of neurology at Georgetown University Medical Center in Washington, DC, says:

"Our novel blood test offers the potential to identify people at risk for progressive cognitive decline and can change how patients, their families and treating physicians plan for and manage the disorder."

Rates of Alzheimer's disease - a condition that gradually clogs up and kills brain cells and leads to memory loss and mental decline - are rising rapidly around the globe. The disease mostly affects older people, although there are rare forms that can start earlier in life.

In 2010, there were 35 million people with Alzheimer's disease worldwide. The World Health Organization (WHO) predicts this number will double every 20 years, rising to 115 million by 2050.

There are currently no treatments that cure or halt the disease, something scientists believe could be due to our inability to detect it before it has progressed to the point where clinical symptoms emerge.

Prof. Federoff explains that while there have been many attempts to produce drugs that slow or reverse Alzheimer's, they have all failed, and one reason could be because the drugs are tested at too late a stage of the disease.

Therefore, he and his colleagues focused on the preclinical stage of the disease, looking for biomarkers or telltale molecules that begin circulating in the blood before the disease takes hold.

Every year for 5 years, the researchers tested memory and mental skills, and blood samples of over 500 participants over the age of 70.

They then took the data of 53 participants who developed Alzheimer's or mild cognitive impairment (MCI) and compared it with 53 who remained cognitively healthy. They used mass spectrometry to analyze the blood samples. This method is used to pinpoint the unique chemical signature of molecules.

They found 10 phospholipids - a type of fat that forms a major component of cell membranes - were present at consistently lower levels in blood samples of most of the group that developed Alzheimer's or MCI. They validated their results in another group of 41 participants.


RMSR® Medical Sales Certification offered by the National Association of Medical Sales Representatives is designed for entry level medical device sales reps. The course covers a wide array of topics pertaining to industry knowledge that candidates need to acquire before applying to medical sales positions.

The course and training helps to develop the industry skills, maximizing the candidates potential and goals, as well as making them feel valued and stimulated in their role when communicating with members of the medical community. By an applicant acquiring medical sales training and a RMSR Certification, it puts him/her in a position of strength and qualifies them for medical sales jobs. Medical knowledge is key in this industry and when communicating with doctors, surgeons, and nurses etc. It is extremely important for representatives to use key terminology pertaining to the medical product he/she will be promoting. The only way to succeed in this industry is to garner actual sales. Doctors and Surgeons will not acknowledge a Sales Rep who is not proficient in essential medical terminology, knowledgeable of medical devices/equipment and the anatomy. For those lacking a solid sales background the RMSR course covers knowledge of medical selling techniques and regulation such as Effective Territory Management, Effective Networking, Medical Sales Ethical & Regulatory Guidelines and more.

The National Association of Medical Sales Representative™(NAMSR) is the largest professional association in the world for Medical Sales Representatives. Through our numerous members, the NAMSR™ provides accredited training, continuing education, information about the industry, up-to-date news, programs to assist medical sales reps in their work, training programs to assist candidates who want to break into the industry and initiatives to improve communication with the medical sales field.

For more information on the NAMSR or the RMSR certification visit www.medicalsalescareer.com or call 800-313-9198

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