This peptide toxin has no homology to any previously reported Nav1.7 blockers such as ProTx-II (0.1 mg vial) (Peptides International product PTX-4450-s). This makes it a very novel toxin to add to the researcher’s toolbox and as a promising drug-discovery aid Peptides International believes this product "has legs"!
In making the announcement, Dr. Michael Pennington, President and Chief Executive Officer, stated that, “we are pleased to offer this distinctive product, μ-SLPTX-Ssm6a, which exhibits our strength in complex peptide synthesis. We believe that researchers investigating Nav1.7 as a target will find this product to be very beneficial in assisting their drug discovery programs forward. ”
1. S. Yang, Y. Xiao, DKang, J Liu, Y Li, E.A.B. Undheim, J.K. Klint, M. Rong, R. Lai, and G.F. King, PNAS, published online before print September 30, 2013, doi:10.1073/