The in-vitro research, currently available on The Spine Journal's website and awaiting publication in an upcoming issue, demonstrated an approximate 100 percent increase in production of key angiogenic factors from osteoblast cells cultured on the Titan Spine surface versus PEEK.
The study, titled "Rough titanium alloys regulate osteoblast production of angiogenic factors," compared the production of osteogenic (bone formation) and angiogenic (blood vessel formation) growth factors by human osteoblast cells cultured on PEEK, smooth titanium alloy, and Titan Spine's roughened titanium alloy surface. The authors of the study, led by Barbara Boyan, Ph.D., Dean of the School of Engineering at Virginia Commonwealth University, concluded that, "This experimental study demonstrates that the [Titan Spine surface] stimulates an angiogenic-osteogenic environment with factors important in bone formation and remodeling. This osteogenic environment may enhance bone formation, implant stability, and fusion."
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The National Association of Medical Sales Representative™
For more information on the NAMSR or the RMSR certification visit www.medicalsalescareer.com or call 800-313-9198