Researchers develop new way to control genes: NAMSR Announces

Scientists have discovered a way to switch genes on or off inside yeast and human cells by controlling the point at which DNA is copied into messenger RNA, according to a study published in the journal ACS Synthetic Biology.
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ARLINGTON, Va. - Sept. 6, 2013 - PRLog -- Researchers from Massachusetts Institute of Technology (MIT) say that this discovery could enable scientists to better understand the role of the genes, make it easier to engineer cells and lead to better drugs and treatments.

The new method is based on a system called CRISPR, which is made up of two components. The first is a protein that "binds to and slices DNA," while the second component is a short strand of RNA that guides the protein to the required location within the genome.

The outcome of the study revealed that once the RNA guide and the Cas9 protein linked inside the target cell, the researchers could accurately target the correct gene and switch on transcription.

Additionally, they were surprised to find that this process could also be used to block gene transcription when aimed at a different area of the gene.

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