New Microfluidic Chip Can Capture Live Tumor Cells in The Blood

ARLINGTON, Va. - Aug. 15, 2013 - PRLog -- Now a team of researchers in China has developed a new microfluidic chip that can quickly and efficiently segregate and capture live circulating tumor cells (CTCs) from a patient's blood, with potential applications for cancer screenings and treatment assessments. The researchers describe their technique in the journalBiomicrofluidics, which is produced by AIP Publishing.

Many currently available devices for detecting CTCs in patients' blood are either too slow for clinical use or have other problems, such as a reduced ability to distinguish between the rare CTCs and more common white blood cells and other non-tumor cells.

The new system captures more than 90 percent of the CTCs, which makes it highly efficient. Overall processing time has also been shortened, thanks in part to a step in which red blood cells are selectively lysed, or broken apart. Lysing the red blood cells diminishes the tendency of blood to clog the system, a common problem that slows processing time in similar CTC filtering devices

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