Treating a Hostile Knee Joint Tampa, Clearwater, St. Petersburg Florida

CLEARWATER, Fla. - May 29, 2013 - PRLog -- Treating a Hostile Knee Joint

 Press Release Tampa Florida

What makes up a hostile knee joint? A hostile knee joint is one in which a catabolic or degenerative environment exists. www.drlox.com.  This occurs as a result of an imbalance between catabolic joint destructive cytokines and repair cytokines and growth factors. Stated another way, there are cytokines which promote knee cartilage repair and there are cytokines which break down the knee cartilage. Cytokines are messenger molecules which exert cell signals in a variety of ways. For instance, collagen the main protein of cartilage extracellular matrix can be broken down by enzymes released under certain cytokine control. The extracellular matrix surrounding the collagen is composed of carbohydrate-protein complexes known as proteoglycans. These also can be broken down by cytokines which trigger their breakdown. The extracellular matrix is the environment surrounding the cartilage cell. Cytokines also regulate the building or repair of cartilage. If more joint cartilage is being broken down then is being repaired, the joint is in a negative state or catabolic state and the result is osteoarthritis. Research continues to provide new clues as to the etiology of why arthritis begins and progresses.

Osteoarthritis has been long known to be induced by trauma, mechanical overload, and more recently genetic factors. Surgery is a form of trauma to the knee joint. The cycle of breakdown is perpetuated by the breakdown products themselves which escalate and continue a viscous cycle. Repair is normally under the influence of the cartilage cell (chondrocyte). The role of stem cells and progenitor cells exerting influence as well has been established. The body's repair process through it's own cell system does not respond adequately for repair to occur, a hostile joint may directly impact this. Research has now shown that adding stem cells and progenitor cells into the injured knee can have a reparative effect. This can also be achieved by biological scaffolds and biological therapies. The key is incorporating this knowledge to impact a hostile joint and overcome the degenerative cascade. Dr. Dennis Lox www.drlox.com a Regenerative Medicine specialist

In the Tampa Bay Florida area, utilizes  Platelet-Rich-Plasma (PRP) and Stem Cell Therapy to address the problems of the hostile knee joint, and promote a reparative environment rather than a degenerative one. Platelet-Rich-Plasma (PRP) uses the patients own platelets that are concentrated to use their growth factors as a positive stimulus. Stem Cell Therapy uses the patients own stem cells to create a healing response. Dr. Lox tailors each patients unique situation to address the problem. Treatment needs to be goal and patient specific in order to reach desired outcomes. Understanding the nature of the problem, is the first step in towards moving forward.

Dr. Dennis Lox www.drlox.com is serving patients in the greater Tampa Bay area including, Clearwater, St. Petersburg, Tampa, New Port Richey, Sarasota and Spring Hill and Orlando.         Dr. Lox has been pleased to provide appointments to accommodate the needs of patients out of the area.