First Refractive Index Detector for UHPLC

HOLMES CHAPEL, U.K. - March 19, 2013 - PRLog -- (Santa Barbara, CA) Wyatt Technology announces the immediate availability of the Optilab UT-rEX (UHPLC refractometer with EXtended range), the first RI detector specifically designed for use with UHPLC systems using columns packed with small beads.

Using a combination of miniaturized components and cutting-edge semiconductor photodiode technology as well as proprietary computer algorithms, the UT-rEX presents a host of instrument firsts:

Besides UV, mass spectrometry and evaporative light scattering, there has been no RI detector available for UHPLC applications until now. The linearity of the UT-rEX over a wide concentration range coupled with its sensitivity to samples that are not UV active, make it an exciting addition to UHPLC.

Due to the extremely small volumes of UHPLC, the dead volume from the UT-rEX is <1.5 µL as compared to 10-20 µL or more from other RI detectors. As a result, the superior resolution from UHPLC columns and instruments will not be compromised with the UT-rEX RI detector.

In addition, there are no range or gain settings. The full range of instrument detection is always present, and the full sensitivity exists over the entire range. The small flow cell and proprietary temperature regulation enable stable RI baselines and RI signals which further enhance the detector’s sensitivity.

The new Optilab UT-rEX can be operated below ambient temperatures as easily as above ambient. No hassle temperature control can be programmed down to 4°C or as high as 50°C. The Optilab UT-rEX is ompatible with all UHPLC systems.

To learn more about Wyatt Technology’s Optilab UT-rEX and its capabilities, please visit www.wyatt.com or email info@wyatt.com.