Holding a Ph.D. in human aging and board certified in neurology, clinical pathology, pain management, anatomic pathology and neurology, Dr. Pappolla and a staff of experts offer a variety of skin, hormone and hair removal treatments at the Aesthetic & Anti-Aging Centers of Houston located near the Texas Medical Center.
With assistance from Dr. Kumar Sambamurti and Dr. KS Jagannatha Rao, Dr. Pappollia, Dr. Pappolla investigated the pathogenesis of Alzheimer's disease and the need to examine a more comprehensive approach in identifying the mechanisms promoting neurodegeneration of brains affected by the indicatory plaques and tangles of Alzheimer's disease. For the completion of this article, Dr. Pappolla utilized his in-depth understanding and ongoing knowledge garnered from his practice of providing botox in Houston to people searching for ways to delay health consequences of the natural aging process.
By studying specific lesions called the NFT and SP lesions that are commonly seen in AD patients, Dr. Pappolla et al asserted we could gain a better understanding of the insidious neuronal and synaptic loss as well as the dramatic cognitive failure associated with this type of progressive dementia.
The article discusses the importance of finding that a certain cholesterol transporter may be the biggest risk factor correlating with the development of Alzheimer's disease. Factors supporting this theory include the association of genes related to metabolic conditions and the ApoE cholesterol transporter as well as the consumption of a diet high in cholesterol and fats.
According to Dr. Pappolla's article, people eating excessive amounts of cholesterol-
Because scientists have yet to perfect the ability to identify the earliest stages of the disease, understanding the whole process involved in the evolution of Alzheimer's disease from genetic markers to empirical evidence is extremely limited. However, Dr. Pappolla and his colleagues propose that the failure for membrane proteins to sustain homeostasis may be the cause of Alzheimer's disease.
Moreover, since amyloid plays a major role in the emergence of other diseases (age-related macular degeneration, for example), further research into the importance of cholesterol, amyloid and specific alleles that appear to be protective against AD may guide scientists towards the identification of medications capable of treating a variety of neurodegenerative diseases.
As medical director of the Aesthetic & Anti-aging Centers, Dr. Pappolla continues to study and research the aging process as well as assist people who desire laser rejuvenation, microdermabrasion, facial fillers and botox in Houston.
Dr. Pappolla and the Aesthetic & Anti-aging Centers of Houston are located at 2646 S. Loop West, Suite 104 in Houston, Texas. His office can be reached at 713-661-0700.