The study aimed to investigate genotoxic potential and acute oral toxicity of OciBest. A standard battery of in vitro genotoxicity tests viz., bacterial reverse mutation assay, chromosome aberration (CA) and micronucleus (MN) test were employed to assess the mutagenic activity. The results showed that OciBest did not cause genotoxicity in any of these tests at the tested concentrations. In the acute oral toxicity study, OciBest did not show any toxic effects to Wistar rats when tested at the maximum testable dose of 5 grams/kg body weight indicating that Ocibest has a therapeutic window greater than 45.
In an earlier published clinical study on 158 subjects, OciBest showed 39 percent improvement in general stress symptoms over and above the placebo group. “The present safety study is in addition to the existing preponderance of scientific evidence that OciBest is both safe and effective,” said the director of research at Natural Remedies.