In order to fully understand the scope of Bharath Balu’s work in the research field, it’s vital to understand a few key scientific characterizations. First, the term “mutagenesis,”
Bharath Balu contributed to research developed to a forward genetic technique called transposon-based insertional mutagenesis, so it’s also vital to altogether cognize the term “transposon,”
Now that it’s clear the nature of Bharath Balu’s scientific research in terms of transposon-based insertional mutagenesis, it’s vital to understand the nature of his contribution. He, along with three other talented research scientists, performed studies and gathered information that will hopefully help unlock further genetic findings about the lethal malaria parasite.
In particular, the abstract of PNAS, Preceedings of the National Academy of Sciences, the prestigious journal which published the results of their findings, notes: “We have developed an efficient transposon-mediated insertional mutagenesis method much needed for high-throughput functional genomics of malaria parasites.” Because of their work, the piggyBac transposition system is able to be utilized as an effectual, random integration tool for large-scale, whole-genome mutagenesis of malaria parasites.
Beyond the noted publication, Bharath Balu( http://bharathbalu1.tumblr.com/