Conducted by researchers at the University of Michigan School of Dentistry, scientists found the chemotherapy drug cyclophosphamide, commonly used to inhibit the growth of tumors, could also in some cases take root in bone marrow and allow cancer cells to grow more easily. Though research has not yet discovered why some cancers like prostate and breast metastasize more easily to bones, the study identified a protein called CCL2 as the culprit and were able to reverse the effect it had in allowing cancer cells to develop in bone marrow. Led by Dr. Laurie McCauley, professor in the department of periodontics and oral medicine, the research has already led to new therapies being developed to fight cancer and their ability to spread to bones. The study was published in a paper called; “Cyclophosphamide Creates a Receptive Microenvironment for Prostate Cancer Skeletal Metastasis” featured in the journal Cancer Research.
Because cancer can becomes more aggressive once it metastasizes in bones, this study opens the door for groundbreaking research and development in cancer prevention and early treatment. As a pioneer in the field of periodontal procedures, Dr. Alex Farnoosh is at the forefront of strategies to maintain oral health in all his patients, including those suffering from the effects of cancer. “Because the teeth and gums reflect a person’s overall health, those suffering from cancer are especially susceptible to advanced problems like gum disease and decay.” Dr. Alex Farnoosh continues, “These problems can cause life long complications even if cancer goes into remission. It is our responsibility to support this research to ensure overall patient wellness.”
About The Total Smile:
The Total Smile was founded by Beverly Hills Periodontist Dr. Alex Farnoosh. Serving patients from around the globe at his Beverly Hills office for over 25 years, Dr. Farnoosh has proven expertise in the field of dentistry and offers many unique cosmetic and surgical services. Dr. Farnoosh specializes in dental implants, laser periodontal surgery, gum and bone grafting and his novel gum bleaching approach for treatment of dark and discolored gums and his lip-lowering treatment for a gummy smile. Dr. Farnoosh has been recognized by the Consumers’ Research Council of America (CRC) as one of America’s top dentists in their annual report since 2008. To learn more about Dr. Farnoosh and how to achieve The Total Smile, visit: www.thetotalsmile.com