1. Latest News
  2. Submit Press Release
  1. PR Home
  2. Latest News
  3. Feeds
  4. Alerts
  5. Submit Free Press Release
  6. Journalist Account
  7. PRNewswire Distribution

3D Biomimetic Scaffolds Support Regeneration of Complex Tissues from Stem Cells

Stem cells can be grown on biocompatible scaffolds to form complex tissues such as bone, cartilage, and muscle for repair and regeneration of damaged or diseased tissue.

 
 
Tissue Engineering Part C, Methods
Tissue Engineering Part C, Methods
PRLog - Jan. 10, 2013 - NEW ROCHELLE, N.Y. -- Contact: Vicki Cohn, Mary Ann Liebert, Inc., (914) 740-2100, ext. 2156, vcohn@liebertpub.com

3D Biomimetic Scaffolds Support Regeneration of Complex Tissues from Stem Cells

New Rochelle, NY, January 10, 2013—Stem cells can be grown on biocompatible scaffolds to form complex tissues such as bone, cartilage, and muscle for repair and regeneration of damaged or diseased tissue. However, to function properly, the cells must often grow in a specific pattern or alignment. An innovative method for creating a stretched polymer scaffold that can support complex tissue architectures is described in an article in Tissue Engineering, Part C, Methods, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers (http://www.liebertpub.com). The article is available on the Tissue Engineering, Part C, Methods website (http://www.liebertpub.com/ten).

Zu-yong Wang and a team of researchers from National University of Singapore, Nanyang Technological University, KK Women's and Children's Hospital, and Duke-NUS Graduate Medical School, in Singapore, developed a reproducible method that involves stretching a polymer thin film to produce scaffolds that can support the growth of human mesenchymal stem cells. The stretching process creates orientated 3-dimensional micro-grooves on the surface of the films, and these formations promote consistent alignment and elongation of stem cells as they grow and develop into tissues on and around the resorbable scaffold.

The authors present their work in the article, "Biomimetic 3D anisotropic geometries by uniaxial stretch of poly(?-caprolactone) films for mesenchymal stem cell proliferation, alignment and myogenic differentiation." (http://online.liebertpub.com/doi/full/10.1089/ten.tec.201...)

“The researchers developed a very elegant method to promote cell behavior," says John Jansen, DDS, PhD, Methods Co-Editor-in-Chief and Professor and Chairman, Department of Biomaterials, Radboud University Nijmegen Medical Center, The Netherlands.

About the Journal
Tissue Engineering
is an authoritative peer-reviewed journal published monthly in print and online in three parts: Part A--the flagship journal; Part B—Reviews; and Part C—Methods. Led by Co-Editors-In-Chief Antonios Mikos, PhD, Louis Calder Professor at Rice University, Houston, TX, and Peter C. Johnson, MD, Vice President, Research and Development, Avery Dennison Medical Solutions of Chicago, IL and President and CEO, Scintellix, LLC, Raleigh, NC, the Journal brings together scientific and medical experts in the fields of biomedical engineering, material science, molecular and cellular biology, and genetic engineering. Tissue Engineering is the Official Journal of the Tissue Engineering & Regenerative Medicine International Society (TERMIS)(http://www.termis.org/). Complete tables of content and a sample issue may be viewed on the Tissue Engineering website (http://www.liebertpub.com/ten).  

About the Publisher
Mary Ann Liebert, Inc., publishers
is a privately held, fully integrated media company known for establishing authoritative peer-reviewed journals in many promising areas of science and biomedical research, including Stem Cells and Development, Human Gene Therapy, and Advances in Wound Care. Its biotechnology trade magazine, Genetic Engineering & Biotechnology News (GEN), was the first in its field and is today the industry’s most widely read publication worldwide. A complete list of the firm’s 70 journals, books, and newsmagazines is available on the Mary Ann Liebert, Inc., publishers website (http://www.liebertpub.com).

Photo:
http://www.prlog.org/12057063/1

--- End ---

Click to Share

Contact Email:
***@liebertpub.com Email Verified
Source:Mary Ann Liebert, Inc., publishers
Phone:914-740-2100
Zip:10801
Location:New Rochelle - New York - United States
Industry:Medical, Science
Tags:regenerative medicine, tissue engineering, cell biology, mesenchymal stem cells, polymer scaffold
Shortcut:prlog.org/12057063
Verified Account Email Address
Verified Account Phone Number

Disclaimer:   Issuers of the press releases are solely responsible for the content of their press releases. PRLog can't be held liable for the content posted by others.   Report Abuse

Latest Press Releases By “

More...

Trending News...



  1. SiteMap
  2. Privacy Policy
  3. Terms of Service
  4. Copyright Notice
  5. About
  6. Advertise
Like PRLog?
9K2K1K
Click to Share