A LoGiCal® success for online SPE-LC/MSMS

PRLog (Press Release) - Nov. 28, 2012 - LoGiCal® reference materials from LGC Standards have enabled specialist instrument manufacturer Spark Holland (https://smtp.kdm-communications.com/exchweb/bin/redir.asp?URL=http://www.sparkholland.com/) in Emmen, the Netherlands, to establish an online SPE-LC/MSMS method for the analysis of synthetic cannabinoids. Business Development Manager Martin Sibum explained: “We develop applications for a variety of markets, including clinical pharma, toxicology and forensics, and are involved in screening for drugs of abuse. The use of designer drugs is on the increase, and we needed to develop a quantitative online SPE-LC/MSMS method for the analysis of synthetic cannabinoids (https://smtp.kdm-communications.com/exchweb/bin/redir.asp...), or ‘Spice’ compounds. These compounds are relatively new, and LGC Standards was quite unique in being able to supply reference standards for five Spice compounds from stock.”

“Availability of these reference materials allowed us to quickly and easily prepare calibration standards for each compound, and to develop an automated SPE method on a Symbiosis™ system. Within two days, we had established an online SPE-LC/MSMS method1 for the quantification of five Spice compounds in urine. This was the first time we had worked with LGC Standards, and we achieved excellent results using LoGiCal reference materials. CVs were less than 5 % – and accuracy within ±10 % – for all compounds and concentrations, with correlation coefficients greater than 0.99. LGC Standards was really helpful and showed an interested in the results, so it was an excellent first collaboration.”

To learn more about the LoGiCal product range, visit www.logical-standards.com (https://smtp.kdm-communications.com/exchweb/bin/redir.asp...)

1 https://smtp.kdm-communications.com/exchweb/bin/redir.asp...

About LGC Standards

LGC Standards (www.lgcstandards.com) provides products and services to improve measurement and quality control within the laboratory, and is part of LGC, whose LGC Science & Technology Division acts as the UK National Measurement Institute for chemical and bioanalytical measurements. LGC Standards supplies over 100,000 products, including reference materials, pharmaceutical impurity reference standards (produced under ISO Guide 34 accreditation), biological standards and reagents, and proficiency testing. LGC Standards is headquartered in Teddington, Middlesex, UK. Its global centre for excellence in proficiency testing is located in Bury (Greater Manchester). LGC Standards has offices in France, Germany, Italy, Poland, South Africa, Spain, Sweden, China, Russia, United Arab Emirates, UK and the US, a joint venture presence in India, and representatives in Brazil, Bulgaria, Czech Republic, Finland, Hungary, Ireland, the Netherlands, Romania and Turkey.

About LGC

LGC (www.lgcgroup.com) is the international science-based company and market leader in analytical, forensic, biotechnology and diagnostic services, as well as diagnostic products, proficiency testing and reference standards. LGC operates in a variety of international markets which underpin the safety, health and security of the public and the regulation of industry, for both public and private sector clients.

LGC has five divisions - LGC Forensics, LGC Genomics, LGC Health Sciences, LGC Standards and LGC Science & Technology. The latter includes specialist laboratories delivering contracts for the Department for Business, Innovation and Skills (BIS) and supports LGC's designated role as the UK's National Measurement Institute for chemical and bioanalytical measurement.

Our operations are extensively accredited to international quality standards such as ISO/IEC 17025. With headquarters in Teddington, South West London, the LGC Group employs over 1,800 staff and operates out of 22 countries, with laboratories and centres across Europe and the US, as well as sites in Brazil, China and India. The genesis of LGC dates back to 1842, and for more than 100 years it has been home to the UK statutory function of Government Chemist. Formerly the Laboratory of the Government Chemist, LGC was privatised in 1996 and is now majority-owned by funds managed by Bridgepoint.

For further information contact:

Amanda Russell

Marketing Manager

LGC Standards

Queens Road, Teddington

Middlesex

TW11 0LY

UK

Tel: +44 (0)20 8943 7412
Fax: +44 (0)20 8943 2767
Email: amanda.russell@lgcstandards.com (mailto:deborah.gaskell@lgcgroup.com)

Web: www.lgcstandards.com

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About Spark Holland: www.sparkholland.com

Spark Holland B.V. is located in Emmen, the Netherlands has been active in development and production of HPLC instruments since 1983. Since then, over 30.000 instruments have been delivered around the world. Spark Holland specializes in innovative integration of sample prep functionality into front-end sample handling systems and introduced such capabilities as pre-column derivatization, column switching and on-line SPE as integrated functions on autosamplers and front-end systems. OEM sales and partnering is a substantial part of the business and Spark Holland offers comprehensive customization of hard- and software. Spark Holland is ISO 13485 and ISO 9001 certified.