Biographer Jill Piercy and New Welsh Review's Gwen Davies will host a centenary evening celebrating Brenda's work, her connections with Alun Lewis and the Caseg Press.
The discussion will also include her poetry, art, books and her life on Bardsey Island, Germany and on the Greek island of Ydra.
Fluellen Theatre company will then present a script in hand performance of extracts from Chamberlain's play The Protagonists.
In her centenary year, Parthian Books have published fiction and drama by Brenda Chamberlain, along with a biography of her life.
The Dylan Thomas Festival continues until 9 November and features Graham Hunter, Paul Durcan, Nigel Jenkins, Menna Elfyn, Ros Barber, Kevin Barry, Roshi Fernando and Fernhill.
Jo Furber Swansea Council’s Literature Officer said "The Dylan Thomas Festival celebrates arts and entertainment including music, theatre, art and prose. We are thrilled to welcome our impressive range of talented guests to the 2012 Festival.
“We expect to attract visitors from across Britain, and as far a field as the USA and Australia”.
Tickets are £6, £4.20 for concessions and £2.40 for PTL. They are available by ringing the Dylan Thomas Centre on 01792 463980 or by visiting http://www.ticketsource.co.uk/