Published in Nature Immunology (March 25, 2012), the study was collaboration between Queen Mary University of London and research teams in the United States. Scientists found that because an older population is more susceptible to chronic inflammatory diseases that produce neutrophil-mediated tissue injury like periodontitis, they closely examined a protein called Del-1. Del-1 works with the immune system to stop white blood cells from attaching and attacking mouth tissue. The defensive properties of Del-1 were revealed as researchers experimented with young and old mice; mice lacking Del-1 exhibited severe gum disease and bone loss in addition to a high amount of white blood cells in the gum tissue, while mice with Del-1 had fewer cases of gum disease and bone loss and a reduced number of white blood cells. Taking these findings into consideration, the study further established that Del-1 tends to decline in individuals as they age. Because this protein is integral to protecting the gums from disease and periodontitis, the lack of Del-1 leaves an individual more vulnerable to oral complications. This opens the door for more research centered on the properties of Del-1 and could establish new ways to better treat gum disease.
As a pioneer in the dental field, Dr. Alex Farnoosh is an expert in fighting advanced periodontal disease and is the founder of revolutionary ways to fight this and a variety of other oral problems. Dr. Alex Farnoosh states, “Studies like this are illuminating and exciting because of what it could mean in keeping our patients healthy and gum disease free. I look forward to more research in this field and the advancements that could develop in the fight against gum disease.”
About The Total Smile:
The Total Smile was founded by Beverly Hills Periodontist Dr. Alex Farnoosh. Serving patients from around the globe at his Beverly Hills office for over 25 years, Dr. Farnoosh has proven expertise in the field of dentistry and offers many unique cosmetic and surgical services. Dr. Farnoosh specializes in dental implants, laser periodontal surgery, gum and bone grafting and his novel gum bleaching approach for treatment of dark and discolored gums and his lip-lowering treatment for a gummy smile. Dr. Farnoosh has been recognized by the Consumers’ Research Council of America (CRC) as one of America’s top dentists in their annual report since 2008. To learn more about Dr. Farnoosh and how to achieve The Total Smile, visit: http://www.thetotalsmile.com