With contributions from a cadre of internationally known experts, the book covers a spectrum of essential topics related to this widespread phenomenon, including:
The relationship between obesity and type 2 diabetes
The addiction mechanism related to refined foods as a significant factor in obesity
The correlation between obesity and environmental estrogens, endocrine disruption, cigarette smoking, and inflammatory response
The role of drug and chemical toxicities and genomic imprinting disorders in obesity
The safety and regulation of prescription and over-the-counter weight loss drugs
Various diets, the glycemic index, and the role of exercise in treating or preventing obesity
Controversy over effective vs. banned weight loss supplements
Childhood obesity and its prevention
Bariatric surgery for weight management and reversal of metabolic disorders
As the public has become more aware of the deadly adverse effects of obesity, numerous products and programs have targeted the overweight and obese population, many with dangerous side effects. It is essential that we develop strategic, therapeutic intervention supported by credible data. This volume is an ideal reference point for researchers looking for new avenues of inquiry and practicing medical professionals, clinical nutritionists, and dietitians seeking guidance for their patients.
Praise for the First Edition
“...Obesity takes a broader perspective. We are treated to short reviews of neurobiology, leptin, and ghrelin as well as chapters on environmental estrogens as endocrine disrupters, smoking and inflammation, and other oxidative stressors that may be contributing to the obesity epidemic. Regarding thereapies, this book has solid chapters on diet and exercise ... on specific “neutraceuticals”
—Margo A. Denke, MD, University of Texas, writing in The New England Journal of Medicine, December 13, 2007
“... this book is not a casual read. It is an in-depth treatise on the epidemiology, pathophysiology, prevention, and treatment of a modern-day epidemic, obesity. It begins with a detailed review of the prevalence and health burden of obesity worldwide and how the current situation has developed over the past 4 decades. ... deals with the pathophysiology of obesity ... natural, nutritional, and physical approaches to weight management. There is very little, if anything, about the many approaches to weight loss that is not addressed ... .
“... This book covers all aspects of obesity. ... the editors maintained an evidence-based approach whenever possible and have maintained an open mind and an impartiality toward controversial issues. They discuss the recent development of drugs ... and the role of vegetarianism, tea, and other natural health products.
“ ... This is a textbook and reference, and it serves that purpose exceptionally well. Graduate students in the field of obesity should read it or at least use it as a reference. ... this book will point them in the right direction and give them an overview about what they need to learn; a lot of that learning can come directly from this book. Practitioners specializing in obesity management and lifestyle issues should have it as a reference, as should obesity researchers.”
—Marshall Godwin, MD, MSc, CCFP, writing in JAMA, 2008;299(17):
About the Authors
Debasis Bagchi is a professor in the Department of Pharmacological and Pharmaceutical Sciences at the University of Houston College of Pharmacy in Texas and the Director of Innovation & Clinical Affairs at Iovate Health Sciences Research Inc., in Oakville, Canada. His research interests include free radicals, human diseases, carcinogenesis, pathophysiology, mechanistic aspects of cytoprotection by antioxidants, and regulatory pathways in obesity, diabetes, and gene expression. He has received funding from various institutions and agencies, including the U.S. Air Force Office of Scientific Research, Nebraska State Department of Health, Biomedical Research Support Grant from National Institutes of Health (NIH), National Cancer Institute (NCI), Health Future Foundation, The Procter & Gamble Company, and Abbott Laboratories. Dr. Bagchi received the Master of the American College of Nutrition Award in 2009. He has authored 287 peer- reviewed publications and 15 books.
Harry G. Preuss is a tenured professor at Georgetown University (Washington, D.C.) in four departments—
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ISBN 9781439854259, July 2012, 1,008 pp