What are the symptoms of hyper-IgM syndrome?
Infants usually develop recurring upper and lower respiratory infections within the first year of life. Other signs of the disease include enlarged tonsils, liver, and spleen, chronic diarrhea, and an increased risk of unusual or opportunistic infections and non-Hodgkin's lymphoma.
How is hyper-IgM syndrome treated?
Patients receive injections of intravenous immunoglobulin (IVIG) every three or four weeks. For neutropenia, patients can take G-CSF, a protein that stimulates the body to produce more granulocytes. Their doctor may also prescribe antibiotics to prevent the lung disease, Pneumocystis carinii pneumonia.
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