Anti-Desmoglein 3 (Dsg3) antibody (catalog # 603-810)
Desmogleins are calcium-binding transmembrane glycoproteins, members of the desmosomal cadherins that provide adhesive integrity to desmosomes between adjoining keratinocytes;
Desmoglein 3 protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris and plays important roles in human squamous cell cancer. The level of Dsg3 can be used as a read-out of pathogenic changes.
Anti-Desmoglein 3 (Dsg3) antibody (catalog # 603-810) has been validated for use in Western blot, and immunohistochemistry on paraffin-embedded human sections.
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