Lyophilization Technology - Webinar By ComplianceOnline

June 3, 2011 - PRLog -- At the end of the session, the attendee will be able to develop a well-defined process for taking an empirical approach to designing formulations and the lyophilization cycles used to dry them. By understanding and applying the principles gained from this webinar, companies have a much greater chance of getting products approved by the Regulatory agencies than those companies that employ the “trial and error” approach to formulation and lyophilization cycle design.

Areas Covered in the Seminar:

- Brief history
- Basic system components
- Temperature and vacuum monitoring devices
- Crystalline vs. amorphous vs. mixed systems
- Eutectic melting, glass transition, and collapse temperatures
- Partial collapse vs. meltback
- Principals of thermal analysis
- Thermal analysis equipment and techniques: DSC, DTA, TEA
- Freeze-dry microscopy equipment and techniques
- Preformulation assessment

Learning Objectives:

- Understanding the different components of a freeze-dryer
- Understanding the correct temperature and vacuum sensing devices for a specific application
- Understanding the thermal properties of a formulation (crystalline, amorphous, mixed)
- Understanding the critical temperatures (Tg', Te, Tc) of a formulation
- Understanding different excipients in formulations and how they affect the thermal properties
- Understanding issues associated with large molecule (monoclonal antibodies, globular proteins, etc)formulation and freeze-drying

Who Will Benefit:

This webinar will provide valuable assistance to those companies involved developing formulations and lyophilization cycles, or in lyophilization product manufacturing.

- Quality Control Scientists
- Development Scientists
- Production Management
- Quality Assurance

For more details:
http://complianceonline.com/ecommerce/control/trainingFoc...