You tear it, you put it on your body, it dries up, and that’s it. The convenience of this new modality, the ease of administration and the attractiveness was that we now have something that the patient can carry in his pocket.
The skin is absolutely a very good medium to absorb medications. So when you absorb it, it appeared in the blood stream in a constant level there was no fluctuation. Another good advantage of the skin as a way of administrating the hormone was that if you felt that it was inappropriate to give it because the patient showed some changes in his biochemistry, you can stop it the following day. If you give the 3 monthly injections, you will have to wait 3 months for the drug to disappear. And if there was any potential problem you could not get rid of it.
1. The first one that we used from time immemorial was the 2 or 3 weekly injections. But the trouble with this method was that it caused a rapid rise in the level and a very precipitous fall which caused the temperament of the male to be sometimes unstable.
2. The next era was the era of the tablet. The tablet was a very quick fix to the problem; very attractive. People though they could take 2 in the morning, 2 at night and it’s wonderful. The problem was that it had to be taken with a fatty meal.
3. The first cream that appeared was a sticky cream. And the sticky cream had to be applied on the body. It had an odour. It created skin allergy it also required you to be living in temperate climate to have it. Otherwise in a humid climate like Singapore it created a lot of problems.
4. The intramuscular 3 monthly injection. When this came about it then became clear that people were prepared to have a single injection every three monthly and if the injection did not cause transient rises and fall of the hormone, which the 3 monthly injections was capable of doing. So it was pretty successful when it was launched.
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About Orient Europharma
Founded in 1982, Orient Europharma (OE, Taiwan OTC: 4120) comprises five divisions: Pharma, Nutricare, Dermo-Cosmetics, Oncology and Consumer Healthcare. The company’s leading products include hyaluronic acid injections and Karihome goat milk for infants and toddlers. Starting in 1993, OE established subsidiaries in Singapore, Hong Kong, Malaysia, and the Philippines. In 2006, OE expanded into mainland China. In 2003, the company listed on Taiwan’s OTC market.
Melinda Ilagan / Jeremy Ee
EASTWEST PR for Orient Europharma
Tel: +65 6222 0306