Infectious Diseases Drugs Markets----Aarkstore Enterprise

PRLog (Press Release) - Feb 25, 2010 -
According to the World Health Organization (WHO), six infectious diseases--pneumonia, tuberculosis, diarrheal diseases, malaria, measles and HIV/AIDS--account for half of all premature deaths worldwide, killing mostly children and young adults. What’s more, threatening pandemics such as swine flu (H1N1 influenza A virus) are adding significant pressure to already strained healthcare budgets of governments around the world. This report provides a detailed description of the current infectious diseases drugs market and highlights the existing and developing anti-infective agents used to ameliorate diseases’ afflictions on humankind. Anti-infective agents include: anti-viral therapeutics, antibiotics, anti-fungal agents and prophylactic treatments such as vaccines. Particular attention is paid to the clinical market segment and the pharmaceutical/biotechnology companies involved in anti-infective agents, with specific emphasis on each company’s sales focus, product portfolio and R&D pipeline. To date, the most successful anti-infective agents target the human immunodeficiency virus (HIV, the virus that causes AIDS), the herpes virus (HSV-1 and HSV-2), bacterial infections and hepatitis C (HCV). A number of exciting novel anti-viral and antibiotic compounds are currently revolutionizing the infectious diseases drugs market, including Truvada and Valtrex, which are anti-HIV and anti-herpes therapies, respectively. Significant resources are also being dedicated toward hepatitis A (HAV), hepatitis B (HBV) and Staph infections, including MRSA. What’s more, this study will examine the existing and developing anti-infective agents targeted at infectious diseases that continue to devastate developing countries, including: cholera, dengue fever, meningitis, rotavirus, typhoid, yellow fever and onchocerciasis (“river blindness”)


 Table of Contents :  
1. Overview 9
1.1 Statement of Report 9
1.2 Scope of the Report 9
1.3 Methodology 10
1.4 Executive Summary 11

2. Clinical Syndromes and Therapy 20
2.1 Head and Neck 22
2.1.1 Sinusitis 22
2.1.2 Pharyngotonsillitis 23
2.1.3 Deep Neck Infections 23
2.1.4 Otitis Media and Externa 23
2.1.5 Acute Suppurative Thyroiditis 23
2.2 Eye 24
2.2.1 Conjunctivitis 24
2.2.2 Keratitis 24
2.2.3 Iritis 24
2.2.4 Retinitis 25
2.2.5 Endophthalmitis 25
2.3 Skin and Lymph Nodes 25
2.3.1 Complicated Skin and Skin Structure Infections (cSSSI) 25
2.3.2 Lymphadenitis 25
2.4 Respiratory Tract 26
2.4.1 Bronchitis 26
2.4.2 Laryngitis 26
2.4.3 Pneumonia 26
2.4.4 Influenza 28
2.4.5 Avian Bird Flu 29
2.4.6 Swine Flu 29
2.4.7 Respiratory Syncytial Virus 33
2.4.8 Tuberculosis 34
2.5 Heart and Blood Vessels 38
2.5.1 Endocarditis 38
2.5.2 Acute Pericarditis 38
2.5.3 Myocarditis 38
2.5.4 Vascular Infection 38
2.6 Gastrointestinal Tract, Liver and Abdomen 39
2.6.1 Acute Viral Hepatitis 39
2.6.2 Chronic Hepatitis 39
2.6.3 Biliary Tract Infection 40
2.6.4 Pancreatitis 41
2.6.5 Esophageal Infections 41
2.6.6 Gastroenteritis 41
2.6.7 Peritonitis 42
2.7 Genitourinary Tract 43
2.7.1 Urethritis 43
2.7.2 Prostatitis 43
2.7.3 Urinary Tract Infection 44
2.7.4 Pelvic Inflammatory Disease 44
2.7.5 Candiduria 44
2.7.6 Human Papilloma Virus 44
2.8 Nervous System 45
2.8.1 Bacterial Meningitis 45
2.8.2 Viral Encephalitis 46
2.8.3 Reye’s Syndrome 46
2.8.4 Myelitis and Peripheral Neuropathy 46
2.9 Musculoskeletal System 46
2.9.1 Osteomyelitis 46
2.9.2 Polyarthritis 47
2.9.3 Bursitis 47
2.9.4 Psoas Abscess 47
2.10 Human Immunodeficiency Virus (HIV) Infection 47
2.11 Blood-borne Infections 53
2.11.1 Malaria 53
2.11.2 West Nile Virus 56

3. Anti-infective Agent Markets 58
3.1 FDA Approvals of New Anti-infective Therapy 60
3.2 Anti-infective Agents in Current Pharmaceutical Developmental Programs 68
3.3 Factors Determining Anti-infective Drug Development 71
3.4 Pharmaceutical R&D Expenditures 71

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