OTAVA has extensive experience in the synthesis of highly valuable products for biotech and pharmaceutical applications around the world. Our company offers various inhibitors, agonists and other biologically active compounds modulating activities of distinct targets. These compounds are available from milligram to gram quantities. Custom and bulk quotes are also available.
OTAVA offers an additional 30% discount on orders of our best selling products. All these compounds are in-stock and available for immediate delivery.
This is a limited time offer available for orders received on or before October 31, 2009.
Bifeprunox
Novel atypical antipsychotic agent which is under development as a treatment for schizophrenia and potentially conditions such as bipolar disorder. It is a partial agonist at D(2)-like receptors and is an efficacious agonist at 5-HT(1A) receptors
CAS RN 350992-10-8
OTAVA catalogue no. 7070707030
PD-0325901
Orally bioavailable mitogenic extracellular kinase 1/2 (MEK1/2) inhibitor
CAS RN 391210-10-9
OTAVA catalogue no. 7070707062
ARRY-142886 (AZD6244)
Orally active, potent, selective MEK inhibitor that blocks signal transduction pathways implicated in cancer cell proliferation and survival. AZD6244 has shown tumour suppressive activity in multiple pre-clinical models of human cancer including melanoma, pancreatic, colon, lung, and breast cancers
CAS RN 606143-52-6
OTAVA catalogue no. 1183194
NSC 74859 (S3I-201)
Inhibitor of STAT3 with anti-tumor activity; NSC 74859 in inhibition of STAT3 dimerization assays demonstrated an IC50 of < 500 µM
CAS RN 501919-59-1
OTAVA catalogue no. 7070707021
For a full list of compounds, please download our catalogue in PDF format:
http://www.otavachemicals.com/
