According to an article on Fierce Biotech, around one third of all people and many animals carry Staphylococcus aureus, which simply lives on most of us as a biofilm fairly harmlessly. Occasionally it causes minor spots on our skin, abscesses and soft tissue infections and some people can get infected over and over again. On much rarer occasions it causes severe and life threatening infections that are significant medical problems. Many of these infections are made worse by the biofilm component of the overall disease, which helps to protect the bacteria from antibiotics.
Staph bacteria tend to grow in cellular communities, particularly on medical devices commonly used on patients, producing what are called biofilm type infections. The devices range from simple catheters placed into blood vessels to those used for blood access for patients on dialysis to artificial heart valves, knees and hips. All patients with these types of devices in them have an increased risk for Staph infections. Living in biofilms protects the bacteria from antibiotics, making treatment more difficult.
"To grow as a biofilm the bacteria must produce sticky factors, one of which is a type of complex sugar called PNAG. We are targeting this material as a possible vaccine, but natural exposure to the sugar compound does not result in most people and animals making an immune response that would protect them from attack by the bacteria or recurring infections,"
By manipulating the sugar chemically the scientists have discovered that they can produce variant forms which can be used as vaccines by causing the right type of immune response, an approach that has already been shown to work successfully in animal studies.
In addition, the researchers have created an antibody with the desired properties to give to people if they have a high risk of getting a Staph infection, thus preventing infection. "This antibody is being manufactured to start tests in humans in about 12 to 18 months," said Professor Pier. "An effective antibody treatment for Staph infections could have a major benefit for anyone who enters a hospital or works in the community and is at risk of Staph infections."
Vital Oxide is proven to fight and eliminate MRSA. Vital Oxide can be used on table top surfaces, counter tops, and other hard surfaces. Please visit www.vitaltechnologies.com for more information on Vital Oxide.
