Excipients Forecasts For 2011 & 2016

PRLog (Press Release) - Jan 30, 2008 -
US demand for pharmaceutical excipients will expand 4.4 percent annually to $3.1 billion in 2011. Growth opportunities will extend to a wide range of compounds and applications. Based on advances in material quality and processing safety, gelatin will remain the dominant compound for drug encapsulation, warding off challenges from more expensive cellulosic and vegetable oil derivatives. Due to the breadth of existing and potential applications in drug formulations and delivery systems, cellulose derivatives will eventually evolve into the top- elling group of pharmaceutical excipients. These compounds will command especially strong growth opportunities as controlled release agents and in specialty uses such as enteric coatings and chewable tablets.
Minerals to be fastest growing excipent product
Ongoing efforts to improve the bioavailability and safety of parenteral and inhalation drugs will boost demand for specialty polymer excipients, especially compounds with sustained- elease and targeting properties. In addition, multifunctional synthetic polymers, such as povidone, will broaden applications in high value-added oral medicines, including disintegrating tablets and controlled-release drug delivery systems. Through 2011, minerals will command the strongest growth in demand value among all pharmaceutical excipients based on a favorable mix of cost and performance properties. Calcium phosphate and calcium carbonate as tablet fillers, titanium dioxide as a tablet coatings, and petrolatum and mineral oils in topical drug suspensions will fare particularly well in the marketplace. Cost and quality advantages will also expand market opportunities for starchbased pharmaceutical  excipients, with pregelatinized starch fillers and binders  and sodium starch glycolate disintegrants commanding the best sales growth. Based on ease of processing advantages and good compacting and compression properties, lactose will retain widespread usage as a tablet filler and diluent. Sorbitol and mannitol will see the strongest demand growth among polyol excipients, the former from uses as a liquid drug diluent, the latter from applications as a diluent in parenteral preparations. Among other pharmaceutical excipients, sterile water and FD&C colors will continue to post the largest sales. Demand for sterile water will increase with upward trends in the development and production of parenteral drugs, especially recombinant DNA and monoclonal antibody preparations. Efforts to reduce drug dispensing errors and strengthen drug anti-counterfeiting safeguards will prompt pharmaceutical producers to expand the use of FD&C colors as well as specialty ink excipients.
Study coverage
Excipients, a new industry study, is available for $4500. It presents historical demand data for 1996, 2001 and 2006 plus forecasts for 2011 and 2016 by excipient product and application. The study also considers market environment factors, evaluates company market share data and profiles 50 US industry competitors.
Table of Contents
Introduction
Executive Summary
1 Summary Table
Market Environment
General
Economic Environment
Demographic Trends
Health Care Trends
Medical Conditions
Health Insurance Trends
National Health Expenditures
Medical Providers
Patient Activity
Pharmaceutical Industry Trends
Regulation
Research & Development
Product Shipments
Therapeutic Classes
Dosage Formulations
Regulatory Status (Ethical & OTC)
Pharmaceutical Excipient Market Overview
Historical Demand Patterns
US Trade
International Markets
LIST OF TABLES & CHARTS:
1 Macroeconomic Environment
2 Population by Age Group
3 Acute Conditions by Type
4 Selected Chronic Conditions by Type
5 National Health Expenditures by Type
6 Selected Medical Providers by Type
7 Selected Patient Activity by Type
8 Pharmaceutical Shipments
by Therapeutic Class
9 Pharmaceutical Shipments
by Dosage Formulation
10 Pharmaceutical Shipments
by Regulatory Classification
11 Pharmaceutical Excipient Demand
Patterns, 1996-2006
12 US Trade in Pharmaceutical Excipients
13 International Pharmaceutical
Excipient Demand
Products
General
Gelatin
Types & Properties
Excipient Applications
Hard Gelatin Capsules
Soft Gelatin Capsules
Binders
Other Gelatin Excipients
Cellulose Derivatives
Microcrystalline Cellulose (MCC)
Hydroxypropyl Methylcellulose (HPMC)
Ethyl Cellulose
Methyl Cellulose
Carboxymethylcellulose
Croscarmellose Sodium
Other Cellulose Derivatives
Synthetic Polymers
Povidone
Acrylic Polymers
Polyethylene Glycol
Other Synthetic Polymers
Minerals
Calcium Phosphate
Mineral Hydrocarbons
Calcium Carbonate
Titanium Dioxide
Silicon Dioxide
Other Mineral Fillers/Diluents
Other Minerals Excipients
Starch Compounds
Pregelatinized Starch
Sodium Starch Glycolate
Other Starch Excipients
Sugars Compounds
Lactose
Sucrose
Other Sugar Excipients
Polyols
Sorbitol
Mannitol
Other Polyol Excipients
Other Pharmaceutical Excipients
Sterile & Purified Water
FD&C Colors
Artificial Sweeteners
Lecithin
Antioxidants
Exudate & Vegetable Gums
Stearate Compounds
Glycerin
Shellac
All Other Excipients
LIST OF TABLES & CHARTS:
1 Pharmaceutical Excipient Demand
by Product Group
Cht Excipient Demand by Product Group, 2006
2 Gelatin Excipient Demand by Application
3 Cellulose Excipient Demand by Compound
Cht Cellulose Excipient Demand
by Compound, 2006
4 Microcrystalline Cellulose (MCC) Excipient
Demand by Application
5 Hydroxypropyl Methylcellulose (HPMC)
Excipient Demand by Application
6 Ethyl Cellulose Excipient
Demand by Application
7 Methyl Cellulose Excipient
Demand by Application
8 Carboxymethylcellulose Excipient
Demand by Application
9 Croscarmellose Sodium Excipient
Demand by Application
10 Other Cellulose Excipient
Demand by Application
11 Synthetic Polymer Excipient
Demand by Compound
Cht Synthetic Polymer Excipient Demand
by Compound, 2006
12 Povidone Excipient Demand by Application
13 Acrylic Polymer Excipient
Demand by Application
14 Polyethylene Glycol (PEG) Excipient
Demand by Application
15 Other Synthetic Polymer Excipient
Demand by Application
16 Mineral Excipient Demand by Compound
17 Calcium Phosphate Excipient
Demand by Application
18 Mineral Hydrocarbon Excipient
Demand by Application
19 Calcium Carbonate Filler/Diluent Demand
20 Titanium Dioxide Coating Demand
21 Silicon Dioxide Excipient
Demand by Application
22 Other Mineral Filler/Diluent Demand
23 Other Mineral Excipient
Demand by Application
24 Starch Excipient Demand by Compound
25 Pregelatinized Starch Excipient
Demand by Application
26 Sodium Starch Glycolate Excipient
Demand by Application
27 Other Starch Excipient
Demand by Application
28 Sugar Excipient Demand by Compound
29 Lactose Excipient Demand by Application
30 Sucrose Excipient Demand by Application
31 Other Sugar Excipient Demand by Application
32 Polyol Excipient Demand by Application
33 Sorbitol Excipient Demand by Application
34 Mannitol Excipient Demand by Application
35 Other Polyol Excipient
Demand by Application
36 Other Pharmaceutical Excipient
Demand by Compound
37 Other Pharmaceutical Excipient
Demand by Application
Applications
General
Fillers/Diluents
Capsules
Binders
Drug Delivery Agents
Suspending/Viscosity Agents
Coatings
Flavorants
Disintegrants
Lubricants
Glidants
Other Applications


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