AnaSpec Announces a Broad Selection of T-Cell Epitopes

PRLog (Press Release) – Jan 21, 2008 – Peptides, used individually, as pools or as libraries, have been used extensively as vaccines in stimulating T cells.1 Once bound to MHC (major histocompatibility complex) molecules, these T cells epitopes can activate CD4 or CD8 T cells.1, 2

AnaSpec has announced the availability of a wide selection of T-Cell Epitopes, available both individually and pooled. Use of these peptides has been reported in journals such as the Journal of Biological Chemistry since 1997.3

Company Info

AnaSpec, Inc. is a leading provider of integrated proteomics solutions to pharmaceutical, biotech, and academic research institutions throughout the world. With a vision for innovation through synergy, AnaSpec focuses on three core technologies: peptides, detection reagents (dyes, assay kits, & antibodies), and combinatorial chemistry.

For more information, visit www.anaspec.com

References:
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4. Sato, N. et al. Proc. Natl. Acad. Sci. 104, 588 (2007).
5. Galibert, L. et al. J. Biol. Chem. 280, 21955 (2005).
6. Komlosh, A. et al. J. Biol. Chem. 276, 30050 (2001).
7. Ben-Shahar, S. et al. J. Biol. Chem. 274, 21963 (1999).
8. Stachowiak, AN. et al. J. Immunol. 177, 2340 (2006).
9. Garrod, KR. et al. J. Immunol. 177, 863 (2006).
10. Baekkevold, ES. et al. J. Exp. Med. 201, 1045 (2005).
11. Kwa, S. et al. J. Immunol. 201, 1045 (2005).
12. Seroogy, CM. et al. J. Immunol. 173, 79 (2004).
13. Dorsam, G. et al. J. Immunol. 171, 3500 (2003).
14. Bard, F. et al. PNAS. 100, 2023 (2003).