Enzymes industry forecasts to 2010 & 2015
US demand for enzymes is forecast to rise over six percent per year to nearly $2 billion in 2010, bolstered by strong gains in important markets such as pharmaceuticals, animal feed and starch processing. Other significant markets such as diagnostics, research and biotechnology, and food and beverages will also experience healthy growth, although a challenging environment in the detergent industry will limit even faster advances. Rapid developments in biotechnology over the past decade have enabled advanced discovery, optimization and manufacturing techniques that are driving development across all aspects of the enzyme industry. New, more efficient and high-value enzyme products are creating a variety of opportunities, even in more mature, established markets such as detergents.
Pharmaceuticals to remain largest market, animal feed fastest growing
Pharmaceuticals will remain the largest enzyme market, due principally to the rapid expansion of the orphan drug market for treating lysosomal storage disorders. However, new advances in cardiovascular thrombolytics, as well as other new treatments, will also support strong gains.
Growth in the starch processing market will continue to accelerate as the rapid expansion of the ethanol industry overshadows and offsets weakness in sweetener production. In the longer term, however, demand growth is expected
to moderate as capacity in the ethanol industry surpasses the congressionally mandated minimums.
Animal feed additives will be the fastest growing market, though the pace will slow from the rapid double digit pace of the past decade as the market matures. Increased interest by the Environmental Protection Agency in chemical emissions from the agricultural industry will help growth in phytase demand eclipse that of other animal feed enzymes as farmers seek ways to reduce phosphate run-off from animal waste.
An aging population will help drive near average gains in the diagnostic market, while ongoing research into biologically-
and beverage enzyme demand will also be strong, supported by the development of new applications, and ongoing strength in dairy and bakery products. In the mature detergent industry, fluctuating raw material prices will limit gains as detergent
manufacturers alter formulations to hold down costs, and demand price cuts from their enzyme suppliers.
Table of Contents
Executive Summary
market Environment
General
Demographic Trends
Macroeconomic Outlook
Consumer Spending
Manufacturing Trends
Food & Beverage Industry Outlook
Agricultural Outlook
National Health Expenditures
Petroleum Industry Overview
Historical Market Trends
Pricing & Product Mix
Environmental/
Intellectual Property Considerations
International Activity
Foreign Trade & US Production
TECHNOLOGY Overview
General
Recombinant DNA Technology
Directed Evolution & Gene Shuffling
Protein Engineering Technology
Molecular Screening & Bioinformatics
Enzyme Immobilization
Extremophilic Enzymes
Enzyme Factories
Markets
General
Pharmaceuticals
Pharmaceutical Industry Outlook
Enzyme Demand
Enzyme Replacement Therapy
Digestive
Cardiovascular Thrombolytics
Other
Starch Processing
Ethanol
Industry Outlook
Enzyme Demand
Sweeteners
Industry Outlook
Enzyme Demand
Food & Beverage Processing
Dairy Products
Industry Outlook
Enzyme Demand
Beverage Processing
Industry Outlook
Enzyme Demand
Bakery Products
Industry Outlook
Enzyme Demand
Other Food & Beverage Enzymes
Research/Biotechnology
Industry Outlook
Enzyme Demand
DNA Amplification/
Cleaning Products
Cleaning Product Industry Outlook
Enzyme Demand
Laundry Detergents
Dishwashing Detergents
& Other Cleaners
Diagnostics
Diagnostic Industry Outlook
Enzyme Demand
Animal Feed
Animal Feed Industry Outlook
Enzyme Demand
Phytase
NSP & Other
Other Enzyme Markets
Textile & Leather
Cosmetics & Toiletries
Biocatalysts
Pulp and Paper
All Other
PRODUCTS
General
Carbohydrases
Alpha Amylases
Glucoamylases
Recombinant Human Glycosidases
Cellulases
Glucose Isomerase
Pectinases
Other
Proteases
Microbial Proteases
Fibrinolytic Proteases
Plasminogen Activators
Other
Rennet/Chymosin
Other Protease
Polymerases
Nucleases
DNases
Other
Lipases
Other
INDUSTRY STRUCTURE
Market Share
Competitive Strategies
Research & Development
Cooperative Agreements
Acquisitions & Divestitures
Manufacturing
Marketing & Distribution
Company Profiles
List of Tables & Charts
Executive Summary
1 Summary Table
Market Environment
1 Demographic Trends
2 Macroeconomic Indicators
3 Personal Consumption Expenditures
4 Manufacturers’
5 Food & Beverage Shipments
6 Agricultural Indicators
7 National Health Expenditures
8 Petroleum Industry Indicators
9 Enzyme Market Trends, 1995-2005 Cht Enzyme Market Trends, 1995-2005
10 Selected Enzyme Pricing Trends
11 US Enzyme Trade
MARKETS
1 Enzyme Markets
Cht Enzyme Demand by Market, 2005
2 Pharmaceutical Shipments
3 Pharmaceutical Enzyme Market
4 Enzyme Replacement
Therapy Demand
5 Cardiovascular Thrombolytic
Enzyme Demand
6 Digestive Enzyme Demand
7 Other Pharmaceutical
Enzyme Demand
8 Starch Processing Enzyme Demand
9 Ethanol Indicators
10 Ethanol Enzyme Demand
11 Sweetener Indicators
12 Sweetener Enzyme Demand
13 Food & Beverage Enzyme Demand
14 Dairy Product Shipments
15 Dairy Product Enzyme Demand
16 Cheese Production Enzyme Demand
17 Other Dairy Enzyme Demand
18 Bakery Product Shipments
19 Bakery Product Enzyme Demand
20 Beverage Shipments
21 Beverage Processing Enzyme Demand
22 Other Food & Beverage Enzyme Demand
23 Research Expenditures
24 Research/Biotech Enzyme Markets
25 DNA Amplification & Sequencing Enzyme Demand
26 Other Research Enzyme Demand
27 Cleaning Product Shipments
28 Cleaning Product Enzyme Market
29 Laundry Detergent Enzyme Demand
30 Dishwashing & Other Detergent Enzyme Demand
31 Diagnostic Product Shipments
32 Diagnostic Enzyme Demand
33 Animal Feed Shipments
34 Animal Feed Enzyme Demand
35 Other Enzyme Markets
36 Textile & Leather Enzyme Demand
37 Cosmetic/Toiletry Enzyme Demand
38 Biocatalyst Enzyme Demand
39 Pulp & Paper Enzyme Demand
40 All Other Enzyme Markets
PRODUCTS
1 Enzyme Demand by Product
Cht Enzyme Demand by Product, 2005
2 Carbohydrase Demand by
Product & Market
3 Alpha Amylase Demand
4 Glucoamylase Demand
5 Recombinant Human
Glycosidase Demand
6 Cellulase Demand
7 Glucose Isomerase Demand
8 Pectinase Demand
9 Other Carbohydrase Demand
10 Protease Demand by Product & Market
11 Microbial Protease Demand
12 Fibrinolytic Protease Demand by Product & Market
13 Rennet/Chymosin Demand
14 Other Protease Demand
15 Polymerase Demand
16 Nuclease Demand by Product & Market
17 DNase Demand
18 Other Nuclease Demand
19 Lipase Demand
20 Other Enzyme Demand
INDUSTRY STRUCTURE
1 US Enzyme Sales by Company, 2005
Cht US Enzyme Market Share, 2005
2 Selected Cooperative Agreements
3 Selected Acquisitions & Divestitures
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